As part of the Center for Membrane and Cell Physiology and Department of Molecular Physiology and Biological Physics and the Department of Cell Biology, the Tamm Lab studies the structure and function of membrane proteins of clinical importance in their natural membrane environment. We study proteins that play key roles in virus infection and their entry into cells and proteins that facilitate exocytosis in neurotransmitter release from neurons in neurological and neurodegenerative diseases and insulin release  from pancreatic β-cells in diabetes. We are particularly interested in the roles that membrane lipids play in the regulation of these proteins.